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Cptm1Hrs
Targeted Allele Detail
Nomenclature
Symbol: Cptm1Hrs
Name: ceruloplasmin; targeted mutation 1, Z Leah Harris
MGI ID: MGI:1857981
Synonyms: Cp-, CpKO
Gene: Cp  Location: Chr3:19957054-20009145 bp, + strand  Genetic Position: Chr3, 6.1 cM, cytoband D
Increase in storage iron content in Cptm1Hrs/Cptm1Hrs liver and spleen

Show the 4 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:57730
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cp Mutation:  5 strains or lines available
References
Original:  J:57730 Harris ZL, et al., Targeted gene disruption reveals an essential role for ceruloplasmin in cellular iron efflux. Proc Natl Acad Sci U S A. 1999 Sep 14;96(19):10812-7
All:  16 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory