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Targeted Allele Detail
Symbol: Zp3tm1Dean
Name: zona pellucida glycoprotein 3; targeted mutation 1, Jurrien Dean
MGI ID: MGI:1857971
Synonyms: Zp3tm1Tra
Gene: Zp3  Location: Chr5:135980099-135988624 bp, + strand  Genetic Position: Chr5, 75.62 cM
Germline Transmission:  Earliest citation of germline transmission: J:36772
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
Mutation detailsA neomycin cassette was inserted into exon 1. In situ hybridization experiments demonstrated an absence of mRNA in oocytes and the protein was undetectable in immunofluorescence experiments on mutant ovaries and oocytes. (J:36772)
Inheritance:    Recessive
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Zp3 Mutation:  25 strains or lines available
Original:  J:36772 Rankin T, et al., Mice homozygous for an insertional mutation in the Zp3 gene lack a zona pellucida and are infertile. Development. 1996 Sep;122(9):2903-10
All:  8 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
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