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Nf2tm1Tyj
Targeted Allele Detail
Nomenclature
Symbol: Nf2tm1Tyj
Name: neurofibromatosis 2; targeted mutation 1, Tyler Jacks
MGI ID: MGI:1857941
Synonyms: Merlin-, Nf2-, Nf2KO2-3
Gene: Nf2  Location: Chr11:4765845-4849536 bp, - strand  Genetic Position: Chr11, 3.0 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:40596
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Nf2 Mutation:  47 strains or lines available
References
Original:  J:40596 McClatchey AI, et al., The Nf2 tumor suppressor gene product is essential for extraembryonic development immediately prior to gastrulation. Genes Dev. 1997 May 15;11(10):1253-65
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory