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Brca1tm1Bhk
Targeted Allele Detail
Nomenclature
Symbol: Brca1tm1Bhk
Name: breast cancer 1; targeted mutation 1, Beverly H Koller
MGI ID: MGI:1857931
Synonyms: B1-, Brca1-, Brca1delta223-763
Gene: Brca1  Location: Chr11:101488764-101551955 bp, - strand  Genetic Position: Chr11, 65.18 cM, cytoband D
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:31571
Parent Cell Line:  E14TG2a (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A neomycin resistance cassette replaced a 1.5 kb genomic fragment containing exon 11. (J:31571)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Brca1 Mutation:  41 strains or lines available
References
Original:  J:31571 Gowen LC, et al., Brca1 deficiency results in early embryonic lethality characterized by neuroepithelial abnormalities. Nat Genet. 1996 Feb;12(2):191-4
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory