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Targeted Allele Detail
Symbol: Mxi1tm1Rdp
Name: MAX interactor 1, dimerization protein; targeted mutation 1, Ronald DePinho
MGI ID: MGI:1857929
Synonyms: mxi1-
Gene: Mxi1  Location: Chr19:53310128-53373293 bp, + strand  Genetic Position: Chr19, 47.53 cM, cytoband D
Germline Transmission:  Earliest citation of germline transmission: J:48236
Parent Cell Line:  WW6 (ES Cell)
Strain of Origin:  STOCK 129/Sv and C57BL/6J and SJL
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
Mutation detailsA targeting vector was designed to eliminate an exon required for the production of two isoforms. Disruption of the locus was confirmed by RT-PCR.
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 7 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mxi1 Mutation:  24 strains or lines available
Original:  J:48236 Schreiber-Agus N, et al., Role of Mxi1 in ageing organ systems and the regulation of normal and neoplastic growth. Nature. 1998 Jun 4;393(6684):483-7
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory