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Foxc2tm1Blh
Targeted Allele Detail
Nomenclature
Symbol: Foxc2tm1Blh
Name: forkhead box C2; targeted mutation 1, Brigid L Hogan
MGI ID: MGI:1857865
Synonyms: Foxc2-, mfh1tm1
Gene: Foxc2  Location: Chr8:121116171-121118895 bp, + strand  Genetic Position: Chr8, 70.33 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:39636
Parent Cell Line:  TL1/TL-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA PGK-neomyin selection cassette replaced all of the coding sequences of the gene. In situ hybridization experiments on sections of homozygous embryos confirmed that no detectable transcript was expressed from this allele. (J:39636)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 11 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Foxc2 Mutation:  0 strains or lines available
References
Original:  J:39636 Winnier GE, et al., The winged helix transcription factor MFH1 is required for proliferation and patterning of paraxial mesoderm in the mouse embryo. Genes Dev. 1997 Apr 1;11(7):926-40
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory