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Targeted Allele Detail
Symbol: Foxc2tm1Blh
Name: forkhead box C2; targeted mutation 1, Brigid L Hogan
MGI ID: MGI:1857865
Synonyms: Foxc2-, mfh1tm1
Gene: Foxc2  Location: Chr8:121116171-121118895 bp, + strand  Genetic Position: Chr8, 70.33 cM
Germline Transmission:  Earliest citation of germline transmission: J:39636
Parent Cell Line:  TL1/TL-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA PGK-neomyin selection cassette replaced all of the coding sequences of the gene. In situ hybridization experiments on sections of homozygous embryos confirmed that no detectable transcript was expressed from this allele. (J:39636)
View phenotypes for all genotypes (concatenated display).
In Mice Carrying this Mutation: 11 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Foxc2 Mutation:  0 strains or lines available
Original:  J:39636 Winnier GE, et al., The winged helix transcription factor MFH1 is required for proliferation and patterning of paraxial mesoderm in the mouse embryo. Genes Dev. 1997 Apr 1;11(7):926-40
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 5.21
The Jackson Laboratory