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Lhx1tm1Bhr
Targeted Allele Detail
Nomenclature
Symbol: Lhx1tm1Bhr
Name: LIM homeobox protein 1; targeted mutation 1, Richard R Behringer
MGI ID: MGI:1857848
Synonyms: Lim-, Lim1-, Limdelta
Gene: Lhx1  Location: Chr11:84518284-84525535 bp, - strand  Genetic Position: Chr11, 51.31 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:24115
Parent Cell Line:  AB1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA genomic fragment containing the entire coding region of the gene was replaced with a neomycin selection cassette. (J:24115)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 111 assay results
In Structures Affected by this Mutation: 17 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Lhx1 Mutation:  14 strains or lines available
References
Original:  J:24115 Shawlot W, et al., Requirement for Lim1 in head-organizer function [see comments]. Nature. 1995 Mar 30;374(6521):425-30
All:  21 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/24/2020
MGI 6.15
The Jackson Laboratory