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Pitx2tm2Sac
Targeted Allele Detail
Nomenclature
Symbol: Pitx2tm2Sac
Name: paired-like homeodomain transcription factor 2; targeted mutation 2, Sally A Camper
MGI ID: MGI:1857846
Synonyms: Pitx2-, Pitx2null
Gene: Pitx2  Location: Chr3:129199878-129219591 bp, + strand  Genetic Position: Chr3, 57.84 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:51160
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 27 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pitx2 Mutation:  13 strains or lines available
References
Original:  J:51160 Gage PJ, et al., Dosage requirement of Pitx2 for development of multiple organs. Development. 1999 Oct;126(20):4643-51
All:  27 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory