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EdarTg(OVE1B)Ove
Transgenic Allele Detail
Nomenclature
Symbol: EdarTg(OVE1B)Ove
Name: ectodysplasin-A receptor; transgene insertion OVE1B, Paul Overbeek
MGI ID: MGI:1857813
Synonyms: EdarTgN(OVE1B)Ove, OVE 1B
Gene: Edar  Location: Chr10:58600789-58675654 bp, - strand  Genetic Position: Chr10, 29.37 cM, cytoband B3
Transgene
origin
Strain of Origin:  (C57BL/6 x C3H)F2
Transgene
description
Transgene Type:    Transgenic
Mutations:    Deletion, Insertion, Inversion
 
Mutation details
Inheritance:    Recessive
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Edar Mutation:  5 strains or lines available
Notes

Phenotypic Similarity to Human Syndrome: hypohidrotic/anhidrotic ectodermal dysplasia (OMIM 305100, 224900, and 129490). Similar phenotypes have also been described in mice for the Tabby allelic series at the Eda locus.

References
Original:  J:10318 Shawlot W, et al., Insertional inactivation of the downless gene in a family of transgenic mice. Mol Biol Med. 1989 Aug;6(4):299-307
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory