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Itga3tm1Jak
Targeted Allele Detail
Nomenclature
Symbol: Itga3tm1Jak
Name: integrin alpha 3; targeted mutation 1, Jordan A Kreidberg
MGI ID: MGI:1857792
Synonyms: alpha3-, alpha3beta1-deficient, alpha 3 beta 1 integrin-deficient
Gene: Itga3  Location: Chr11:95044474-95076801 bp, - strand  Genetic Position: Chr11, 59.01 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:36831
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    A neomycin resistance cassette was inserted into the site that corresponds to cDNA nucleotide 1065. (J:36831)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 33 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Itga3 Mutation:  13 strains or lines available
References
Original:  J:36831 Kreidberg JA, et al., Alpha 3 beta 1 integrin has a crucial role in kidney and lung organogenesis. Development. 1996 Nov;122(11):3537-47
All:  23 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory