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Targeted Allele Detail
Symbol: Ggt1tm1Zuk
Name: gamma-glutamyltransferase 1; targeted mutation 1, Martin M Matzuk
MGI ID: MGI:1857766
Synonyms: GGT-, GGTm1, GGTtm1mwl
Gene: Ggt1  Location: Chr10:75561604-75586200 bp, + strand  Genetic Position: Chr10, 38.55 cM
Gross and histologic analysis of wild-type and Ggt1tm1Zuk/Ggt1tm1Zuk mice.

Show the 1 phenotype image(s) involving this allele.

Germline Transmission:  Earliest citation of germline transmission: J:34309
Parent Cell Line:  AB2.1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsAn hprt expression cassette replaced 3kb of 5' sequence, including exons I, 1 and 2, and intervening intronic sequences. (J:34309)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ggt1 Mutation:  27 strains or lines available
Original:  J:34309 Lieberman MW, et al., Growth retardation and cysteine deficiency in gamma-glutamyl transpeptidase-deficient mice. Proc Natl Acad Sci U S A. 1996 Jul 23;93(15):7923-6
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
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