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Rac1tm1Jms
Targeted Allele Detail
Nomenclature
Symbol: Rac1tm1Jms
Name: RAS-related C3 botulinum substrate 1; targeted mutation 1, Institute of Medical Science, Japan
MGI ID: MGI:1857700
Gene: Rac1  Location: Chr5:143505478-143528036 bp, - strand  Genetic Position: Chr5, 82.22 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:52224
Parent Cell Line:  CCE/EK.CCE (ES Cell)
Strain of Origin:  129S/SvEv-Gpi1c
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neo-gpt cassette replaced a genomic fragment containing exons E1 and E2. These exons encode amino acids 97-192 of the protein. (J:52224)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rac1 Mutation:  11 strains or lines available
References
Original:  J:52224 Sugihara K, et al., Rac1 is required for the formation of three germ layers during gastrulation. Oncogene. 1998 Dec 31;17(26):3427-33
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/17/2015
MGI 5.21
The Jackson Laboratory