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Smad2tm2Enl
Targeted Allele Detail
Nomenclature
Symbol: Smad2tm2Enl
Name: SMAD family member 2; targeted mutation 2, En Li
MGI ID: MGI:1857693
Synonyms: Smad2mh2-lacZ
Gene: Smad2  Location: Chr18:76241580-76310963 bp, + strand  Genetic Position: Chr18, 51.42 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:48467
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
    An IRES Beta-geo cassette replaced exon 8, which encodes amino acids 267 - 333. (J:48467)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Smad2 Mutation:  16 strains or lines available
References
Original:  J:48467 Nomura M, et al., Smad2 role in mesoderm formation, left-right patterning and craniofacial development [see comments]. Nature. 1998 Jun 25;393(6687):786-90
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/26/2020
MGI 6.15
The Jackson Laboratory