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Arnttm1Mcs
Targeted Allele Detail
Nomenclature
Symbol: Arnttm1Mcs
Name: aryl hydrocarbon receptor nuclear translocator; targeted mutation 1, M Celeste Simon
MGI ID: MGI:1857680
Synonyms: Arnt-, Arnt(-)
Gene: Arnt  Location: Chr3:95434388-95497240 bp, + strand  Genetic Position: Chr3, 40.74 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:39730
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA PGK-neomycin resistance cassette was inserted into the exon that encodes the basic-helix-loop-helix domain. (J:39730)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Arnt Mutation:  15 strains or lines available
References
Original:  J:39730 Maltepe E, et al., Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT. Nature. 1997 Mar 27;386(6623):403-7
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/05/2019
MGI 6.14
The Jackson Laboratory