About   Help   FAQ
Tgfb1tm1N
Targeted Allele Detail
Nomenclature
Symbol: Tgfb1tm1N
Name: transforming growth factor, beta 1; targeted mutation 1, National Institutes of Health
MGI ID: MGI:1857671
Synonyms: Tgfb1-, TGF-beta1-
Gene: Tgfb1  Location: Chr7:25687002-25705077 bp, + strand  Genetic Position: Chr7, 13.98 cM
Histopathological analysis on lung and heart tissues of Tgfb1tm1N/Tgfb1tm1N mice

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:50848
Parent Cell Line:  CCE/EK.CCE (ES Cell)
Strain of Origin:  129S/SvEv-Gpi1c
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Mice Carrying this Mutation: 5 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tgfb1 Mutation:  14 strains or lines available
References
Original:  J:50848 Kulkarni AB, et al., Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death. Proc Natl Acad Sci U S A. 1993 Jan 15;90(2):770-4
All:  64 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/09/2014
MGI 5.20
The Jackson Laboratory