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Il7tm1Dnax
Targeted Allele Detail
Nomenclature
Symbol: Il7tm1Dnax
Name: interleukin 7; targeted mutation 1, DNAX Research Institute of Cellular and Molecular Biology
MGI ID: MGI:1857652
Synonyms: Il7-, IL-7-
Gene: Il7  Location: Chr3:7569994-7613760 bp, - strand  Genetic Position: Chr3, 2.02 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:24165
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A neomycin resistance cassette replaced all of exon 4 and 300 bp of flanking sequence. (J:24165)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 24 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Il7 Mutation:  18 strains or lines available
References
Original:  J:24165 von Freeden-Jeffry U, et al., Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine. J Exp Med. 1995 Apr 1;181(4):1519-26
All:  89 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory