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Hand2tm1Dsr
Targeted Allele Detail
Nomenclature
Symbol: Hand2tm1Dsr
Name: heart and neural crest derivatives expressed transcript 2; targeted mutation 1, Deepak Srivastava
MGI ID: MGI:1857639
Synonyms: dHANDnull
Gene: Hand2  Location: Chr8:57320983-57324633 bp, + strand  Genetic Position: Chr8, 29.8 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:40768
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A neomycin resistance cassette replaced the entire gene. (J:40768)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 43 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hand2 Mutation:  2 strains or lines available
References
Original:  J:40768 Srivastava D, et al., Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND [see comments] [published erratum appears in Nat Genet 1997 Aug;16(4):410]. Nat Genet. 1997 Jun;16(2):154-60
All:  19 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory