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Phc1tm1Os
Targeted Allele Detail
Nomenclature
Symbol: Phc1tm1Os
Name: polyhomeotic-like 1 (Drosophila); targeted mutation 1, Osaka University Medical School
MGI ID: MGI:1857629
Synonyms: rae28 -
Gene: Phc1  Location: Chr6:122317738-122340506 bp, - strand  Genetic Position: Chr6, 57.52 cM, cytoband F3
Phc1tm1Os/Phc1tm1Os hearts show abnormal cardiac looping at E9.5

Show the 1 image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:43764
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (knock-out)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 71 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Phc1 Mutation:  45 strains or lines available
References
Original:  J:43764 Takihara Y, et al., Targeted disruption of the mouse homologue of the Drosophila polyhomeotic gene leads to altered anteroposterior patterning and neural crest defects. Development. 1997 Oct;124(19):3673-82
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory