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Crabp1tm1Adg
Targeted Allele Detail
Nomenclature
Symbol: Crabp1tm1Adg
Name: cellular retinoic acid binding protein I; targeted mutation 1, Ad Guerts van Kessel
MGI ID: MGI:1857621
Gene: Crabp1  Location: Chr9:54764748-54773110 bp, + strand  Genetic Position: Chr9, 29.76 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:22943
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA genomic fragment containing exons 1 and 2 was replaced with a hygromycin selection cassette inserted in reverse transcriptional orientation relative to the gene. RT-PCR and northern blot analysis on RNA derived from homozygous embryos confirmed that no detectable transcripts were produced from this allele. (J:22943)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 4 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Crabp1 Mutation:  5 strains or lines available
References
Original:  J:22943 de Bruijn DR, et al., Normal development, growth and reproduction in cellular retinoic acid binding protein-I (CRABPI) null mutant mice. Differentiation. 1994 Dec;58(2):141-8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory