Crabp1^tm1Adg
Targeted Allele Detail

Summary

• Symbol: Crabp1^tm1Adg
• Name: cellular retinoic acid binding protein I; targeted mutation 1, Ad Guerts van Kessel
• MGI ID: MGI:1857621
• Gene: Crabp1 Location: Chr9:54672032-54680394 bp, + strand Genetic Position: Chr9, 29.76 cM
• Alliance: Crabp1^tm1Adg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:22943
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A genomic fragment containing exons 1 and 2 was replaced with a hygromycin selection cassette inserted in reverse transcriptional orientation relative to the gene. RT-PCR and northern blot analysis on RNA derived from homozygous embryos confirmed that no detectable transcripts were produced from this allele. (J:22943)

Expression

In Mice Carrying this Mutation:

4 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Crabp1 Mutation: 17 strains or lines available

References

• Original: J:22943 de Bruijn DR, et al., Normal development, growth and reproduction in cellular retinoic acid binding protein-I (CRABPI) null mutant mice. Differentiation. 1994 Dec;58(2):141-8
• All: 1 reference(s)