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Gata1tm1Sho
Targeted Allele Detail
Nomenclature
Symbol: Gata1tm1Sho
Name: GATA binding protein 1; targeted mutation 1, Stuart Orkin
MGI ID: MGI:1857600
Synonyms: GATA-1-
Gene: Gata1  Location: ChrX:7959260-7978071 bp, - strand  Genetic Position: ChrX, 3.59 cM, cytoband A2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:36249
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin selection cassette replaced a genomic fragment containing sequences between the initiation codon in exon 2 and an EcoRI site in exon 3. (J:36249)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 4 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gata1 Mutation:  39 strains or lines available
References
Original:  J:36249 Fujiwara Y, et al., Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1. Proc Natl Acad Sci U S A. 1996 Oct 29;93(22):12355-8
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/10/2017
MGI 6.10
The Jackson Laboratory