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Hoxa2tm1Grid
Targeted Allele Detail
Nomenclature
Symbol: Hoxa2tm1Grid
Name: homeobox A2; targeted mutation 1, Tom Gridley
MGI ID: MGI:1857530
Synonyms: Hox1.11, Hoxa-2-, Hoxa2delta1
Gene: Hoxa2  Location: Chr6:52162417-52164831 bp, - strand  Genetic Position: Chr6, 25.4 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:16389
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsReplacement of 159 bp of exon 1, intron 1 and the first 33 bp of exon 2 with a neomycin resistance cassette. (J:16389)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 66 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hoxa2 Mutation:  5 strains or lines available
References
Original:  J:16389 Gendron-Maguire M, et al., Hoxa-2 mutant mice exhibit homeotic transformation of skeletal elements derived from cranial neural crest. Cell. 1993 Dec 31;75(7):1317-31
All:  18 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory