Mycn^tm1Par
Targeted Allele Detail

Summary

• Symbol: Mycn^tm1Par
• Name: v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived; targeted mutation 1, Luis Parada
• MGI ID: MGI:1857492
• Synonyms: N-myc^-, N-myc^BRP
• Gene: Mycn Location: Chr12:12986094-12991837 bp, - strand Genetic Position: Chr12, 6.14 cM, cytoband A3-B
• Alliance: Mycn^tm1Par page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:48400
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• A neomycin cassette was inserted into exon 3. (J:48400)

Expression

In Mice Carrying this Mutation:	2 assay results
In Structures Affected by this Mutation:	21 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mycn Mutation: 24 strains or lines available

References

• Original: J:48400 Stanton BR, et al., Germ line transmission of an inactive N-myc allele generated by homologous recombination in mouse embryonic stem cells. Mol Cell Biol. 1990 Dec;10(12):6755-8
• All: 4 reference(s)