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Ptch1tm1Mps
Targeted Allele Detail
Nomenclature
Symbol: Ptch1tm1Mps
Name: patched homolog 1; targeted mutation 1, Matthew P Scott
MGI ID: MGI:1857447
Synonyms: LacZ/Ptc, ptc-, Ptc1-, Ptc1-lacZ, Ptc1lzki, Ptch-, Ptch1-, Ptch1-lacZ, PtchKO1, PtchlacZ, ptc-lacZ, PtclacZ, Ptcn
Gene: Ptch1  Location: Chr13:63511533-63565520 bp, - strand  Genetic Position: Chr13, 32.8 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:42441
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 195 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Ptch1 Mutation:  22 strains or lines available
References
Original:  J:42441 Goodrich LV, et al., Altered neural cell fates and medulloblastoma in mouse patched mutants. Science. 1997 Aug 22;277(5329):1109-13
All:  200 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory