About   Help   FAQ
Hexbtm1Rlp
Targeted Allele Detail
Nomenclature
Symbol: Hexbtm1Rlp
Name: hexosaminidase B; targeted mutation 1, Richard L Proia
MGI ID: MGI:1857438
Synonyms: Hexb-, Sandhoff hexb-
Gene: Hexb  Location: Chr13:97176332-97198357 bp, - strand  Genetic Position: Chr13, 50.66 cM
Peripheral monocytes/macrophages are seen in the central nervous system of Hexbtm1Rlp/Hexbtm1Rlp mice

Show the 10 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:29268
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation details
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Mice Carrying this Mutation: 114 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Hexb Mutation:  64 strains or lines available
References
Original:  J:29268 Sango K, et al., Mouse models of Tay-Sachs and Sandhoff diseases differ in neurologic phenotype and ganglioside metabolism. Nat Genet. 1995 Oct;11(2):170-6
All:  34 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/09/2014
MGI 5.19
The Jackson Laboratory