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Col4a3tm1Dec
Targeted Allele Detail
Nomenclature
Symbol: Col4a3tm1Dec
Name: collagen, type IV, alpha 3; targeted mutation 1, Dominic Cosgrove
MGI ID: MGI:1857432
Gene: Col4a3  Location: Chr1:82586921-82722059 bp, + strand  Genetic Position: Chr1, 42.32 cM
Sostdc1tm1Myan/Sostdc1tm1Myan Col4a3tm1Dec/Col4a3tm1Dec mice show less glomerular and tubular injury than Col4a3tm1Dec/Col4a3tm1Dec mice

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:37963
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Col4a3 Mutation:  5 strains or lines available
References
Original:  J:37963 Cosgrove D, et al., Collagen COL4A3 knockout: a mouse model for autosomal Alport syndrome. Genes Dev. 1996 Dec 1;10(23):2981-92
All:  36 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory