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Rb1tm1Brd
Targeted Allele Detail
Nomenclature
Symbol: Rb1tm1Brd
Name: RB transcriptional corepressor 1; targeted mutation 1, Allan Bradley
MGI ID: MGI:1857339
Synonyms: Rb-, Rb-1delta20
Gene: Rb1  Location: Chr14:73194453-73325885 bp, - strand  Genetic Position: Chr14, 38.73 cM, cytoband D3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:2516
Parent Cell Line:  AB1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    Insertion of a neomycin cassette into exon 20. (J:2516)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 34 assay results
In Structures Affected by this Mutation: 11 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rb1 Mutation:  80 strains or lines available
References
Original:  J:2516 Lee EY, et al., Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis [see comments]. Nature. 1992 Sep 24;359(6393):288-94
All:  19 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory