Ednrb^s-1Chlc
Chemically induced Allele Detail

Summary

• Symbol: Ednrb^s-1Chlc
• Name: endothelin receptor type B; chlorambucil 1Chlc
• MGI ID: MGI:1857326
• Synonyms: Ednrb^s-11R, s^1ChLc, s^OR-9Q
• Gene: Ednrb Location: Chr14:104052061-104081838 bp, - strand Genetic Position: Chr14, 53.05 cM
• Alliance: Ednrb^s-1Chlc page

Mutation origin

• Strain of Origin: (101/Rl x C3H/Rl)F1

Mutation description

• Allele Type: Chemically induced (other)
• Mutation: Undefined
• Mutation details: No molecular defect was detected. These mice produce normal levels of transcript in adult brain, suggesting that the mutation affects important regulatory elements that mediate the expression of the gene during development. No genomic alterations identified within ~ 1.25 megabases surrounding the locus. (J:44601)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ednrb Mutation: 103 strains or lines available

References

• Original: J:10322 Rinchik EM, et al., Genetic and molecular analysis of chlorambucil-induced germ-line mutations in the mouse. Proc Natl Acad Sci U S A. 1990 Feb;87(4):1416-20
• All: 4 reference(s)