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Plaurtm1Jld
Targeted Allele Detail
Nomenclature
Symbol: Plaurtm1Jld
Name: plasminogen activator, urokinase receptor; targeted mutation 1, Jay L Degen
MGI ID: MGI:1857290
Synonyms: Plaurtm1, uPAR-
Gene: Plaur  Location: Chr7:24462484-24475968 bp, + strand  Genetic Position: Chr7, 10.92 cM, cytoband A3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:26874
Parent Cell Line:  E14TG2a (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 3, encoding the second half of the amino-terminal uPA binding domain, was replaced by an HPRT minigene. (J:26874)
Inheritance:    Recessive
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Plaur Mutation:  5 strains or lines available
References
Original:  J:26874 Bugge TH, et al., The receptor for urokinase-type plasminogen activator is not essential for mouse development or fertility. J Biol Chem. 1995 Jul 14;270(28):16886-94
All:  28 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory