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Ifngr1tm1Agt
Targeted Allele Detail
Nomenclature
Symbol: Ifngr1tm1Agt
Name: interferon gamma receptor 1; targeted mutation 1, Michel Aguet
MGI ID: MGI:1857286
Synonyms: G129, IFN-gamma R-, IFN-gammaR-, IFN-gamma R0, IFN-gammaR0, IFN-gammaR1-, IFN-gammaRalpha_, IFN-gamma-R KO, IFN-gammaR KO, IFNgammaR KO, Ifngr-, Ifngr1-, IFNgR KO, IFn type II receptor
Gene: Ifngr1  Location: Chr10:19591949-19610229 bp, + strand  Genetic Position: Chr10, 8.49 cM
Trpm2tm1.1Alp/Trpm2tm1.1Alp and Ifngr1tm1Agt/Ifngr1tm1Agt mice exhibit increased susceptibility to bacterial infection

Show the 3 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:63815
Parent Cell Line:  AB1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation details
Inheritance:    Recessive
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 5 strains available      Cell Lines: 0 lines available
Carrying any Ifngr1 Mutation:  8 strains or lines available
References
Original:  J:63815 Huang S, et al., Immune response in mice that lack the interferon-gamma receptor [see comments]. Science. 1993 Mar 19;259(5102):1742-5
All:  377 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory