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Wt1tm1Jae
Targeted Allele Detail
Nomenclature
Symbol: Wt1tm1Jae
Name: Wilms tumor 1 homolog; targeted mutation 1, Rudolf Jaenisch
MGI ID: MGI:1857268
Synonyms: wt1-
Gene: Wt1  Location: Chr2:105126529-105173616 bp, + strand  Genetic Position: Chr2, 55.06 cM, cytoband E
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:14317
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exon 1 and 0.5kb of upstream sequence were replaced with a neomycin selection cassette. (J:14317)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 81 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Wt1 Mutation:  8 strains or lines available
References
Original:  J:14317 Kreidberg JA, et al., WT-1 is required for early kidney development. Cell. 1993 Aug 27;74(4):679-91
All:  38 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory