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Ttrtm1Wsb
Targeted Allele Detail
Nomenclature
Symbol: Ttrtm1Wsb
Name: transthyretin; targeted mutation 1, William S Blaner
MGI ID: MGI:1857264
Synonyms: ttr-, TTR KO
Gene: Ttr  Location: Chr18:20665250-20674324 bp, + strand  Genetic Position: Chr18, 11.47 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:4183
Parent Cell Line:  CCE/EK.CCE (ES Cell)
Strain of Origin:  129S/SvEv-Gpi1c
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ttr Mutation:  23 strains or lines available
References
Original:  J:4183 Episkopou V, et al., Disruption of the transthyretin gene results in mice with depressed levels of plasma retinol and thyroid hormone. Proc Natl Acad Sci U S A. 1993 Mar 15;90(6):2375-9
All:  33 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory