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Tgfb1tm1Doe
Targeted Allele Detail
Nomenclature
Symbol: Tgfb1tm1Doe
Name: transforming growth factor, beta 1; targeted mutation 1, Thomas Doetschman
MGI ID: MGI:1857258
Synonyms: Tgfb1-, TGFbeta1
Gene: Tgfb1  Location: Chr7:25687002-25705077 bp, + strand  Genetic Position: Chr7, 13.98 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:2892
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 4 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 4 strains available      Cell Lines: 0 lines available
Carrying any Tgfb1 Mutation:  14 strains or lines available
References
Original:  J:2892 Shull MM, et al., Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease. Nature. 1992 Oct 22;359(6397):693-9
All:  60 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory