About   Help   FAQ
Mgat1tm1Jxm
Targeted Allele Detail
Nomenclature
Symbol: Mgat1tm1Jxm
Name: mannoside acetylglucosaminyltransferase 1; targeted mutation 1, Jamey Marth
MGI ID: MGI:1857217
Gene: Mgat1  Location: Chr11:49135018-49153854 bp, + strand  Genetic Position: Chr11, 29.27 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:68330
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA neomycin cassette was inserted into the single protein coding exon. No protein activity was detectable in protein extracts derived from homozyogous mutant embryos. (J:68330)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 5 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mgat1 Mutation:  12 strains or lines available
References
Original:  J:68330 Metzler M, et al., Complex asparagine-linked oligosaccharides are required for morphogenic events during post-implantation development. EMBO J. 1994 May 1;13(9):2056-65
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/23/2021
MGI 6.17
The Jackson Laboratory