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Insrtm1Dac
Targeted Allele Detail
Nomenclature
Symbol: Insrtm1Dac
Name: insulin receptor; targeted mutation 1, Domenico Accili
MGI ID: MGI:1857204
Synonyms: Insr-, IR-, IRKO, L1
Gene: Insr  Location: Chr8:3150922-3279617 bp, - strand  Genetic Position: Chr8, 1.82 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:33408
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (knock-out)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 10 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Insr Mutation:  31 strains or lines available
References
Original:  J:33408 Accili D, et al., Early neonatal death in mice homozygous for a null allele of the insulin receptor gene. Nat Genet. 1996 Jan;12(1):106-9
All:  44 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory