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Targeted Allele Detail
Symbol: Inhatm1Bay
Name: inhibin alpha; targeted mutation 1, Baylor College of Medicine
MGI ID: MGI:1857202
Synonyms: INH-, Inha-, inham1, Inhatm1Zuk
Gene: Inha  Location: Chr1:75483721-75487010 bp, + strand  Genetic Position: Chr1, 39.16 cM, cytoband C5
Alliance: Inhatm1Bay page
Liver and stomach histology of Inhatm1Bay/Inhatm1Bay mice

Show the 2 phenotype image(s) involving this allele.

Germline Transmission:  Earliest citation of germline transmission: J:3315
Parent Cell Line:  AB2.1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA PGK-hprt expression cassette replaced two exons of the Inha gene. The authors predict that homozygous mutant mice would not synthesize Inha mRNA or protein. (J:3315)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 8 anatomical structures
Tumor Data
List all tumor models in MMHCdb carrying Inhatm1Bay
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Inha Mutation:  8 strains or lines available
Original:  J:3315 Matzuk MM, et al., Alpha-inhibin is a tumour-suppressor gene with gonadal specificity in mice. Nature. 1992 Nov 26;360(6402):313-9
All:  43 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.22
The Jackson Laboratory