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Inhatm1Bay
Targeted Allele Detail
Nomenclature
Symbol: Inhatm1Bay
Name: inhibin alpha; targeted mutation 1, Baylor College of Medicine
MGI ID: MGI:1857202
Synonyms: INH-, Inha-, inham1, Inhatm1Zuk
Gene: Inha  Location: Chr1:75483721-75487010 bp, + strand  Genetic Position: Chr1, 39.16 cM, cytoband C5
Liver and stomach histology of Inhatm1Bay/Inhatm1Bay mice

Show the 2 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:3315
Parent Cell Line:  AB2.1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA PGK-hprt expression cassette replaced two exons of the Inha gene. The authors predict that homozygous mutant mice would not synthesize Inha mRNA or protein. (J:3315)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 8 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Inha Mutation:  8 strains or lines available
References
Original:  J:3315 Matzuk MM, et al., Alpha-inhibin is a tumour-suppressor gene with gonadal specificity in mice. Nature. 1992 Nov 26;360(6402):313-9
All:  42 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/30/2021
MGI 6.17
The Jackson Laboratory