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Il4tm1Cgn
Targeted Allele Detail
Nomenclature
Symbol: Il4tm1Cgn
Name: interleukin 4; targeted mutation 1, University of Cologne
MGI ID: MGI:1857194
Synonyms: IL-4-, IL4-, IL-4KO, IL-4 KO, IL4T, IL-4T-, IL4tm1cgn129
Gene: Il4  Location: Chr11:53602982-53618669 bp, - strand  Genetic Position: Chr11, 31.97 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:704
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA translational stop codon and a neomycin resistance gene were inserted into the first exon of the gene. (J:704)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 5 strains available      Cell Lines: 0 lines available
Carrying any Il4 Mutation:  24 strains or lines available
References
Original:  J:704 Kuhn R, et al., Generation and analysis of interleukin-4 deficient mice. Science. 1991 Nov 1;254(5032):707-10
All:  184 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/12/2018
MGI 6.12
The Jackson Laboratory