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Hexatm1Rlp
Targeted Allele Detail
Nomenclature
Symbol: Hexatm1Rlp
Name: hexosaminidase A; targeted mutation 1, Richard L Proia
MGI ID: MGI:1857181
Synonyms: Hexa-, Tay-Sachs, Tay-Sachs hexa-
Gene: Hexa  Location: Chr9:59539667-59565105 bp, + strand  Genetic Position: Chr9, 32.02 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:21008
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 2 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Hexa Mutation:  5 strains or lines available
References
Original:  J:21008 Yamanaka S, et al., Targeted disruption of the Hexa gene results in mice with biochemical and pathologic features of Tay-Sachs disease. Proc Natl Acad Sci U S A. 1994 Oct 11;91(21):9975-9
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory