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Fyntm1Sor
Targeted Allele Detail
Nomenclature
Symbol: Fyntm1Sor
Name: Fyn proto-oncogene; targeted mutation 1, Philippe Soriano
MGI ID: MGI:1857172
Synonyms: fyn-
Gene: Fyn  Location: Chr10:39368855-39565381 bp, + strand  Genetic Position: Chr10, 20.51 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:2242
Parent Cell Line:  AB1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Replacement of a 3kb fragment containing the first coding exon of the gene with a neomycin cassette. (J:2242, J:97095)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 6 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Fyn Mutation:  12 strains or lines available
References
Original:  J:2242 Stein PL, et al., pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells. Cell. 1992 Sep 4;70(5):741-50
All:  126 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory