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Cxcr2tm1Mwm
Targeted Allele Detail
Nomenclature
Symbol: Cxcr2tm1Mwm
Name: chemokine (C-X-C motif) receptor 2; targeted mutation 1, Mark Moore
MGI ID: MGI:1857153
Synonyms: Cmkar2tm1Mwm, Cmkartm1Mwm, CXCR-, CXCR2 -, CXCR2-, Il8rbtm1Mwm, mCXCR-, mCXCR2-, mIL-8Rh-, mIL-8Rh KO
Gene: Cxcr2  Location: Chr1:74153991-74161246 bp, + strand  Genetic Position: Chr1, 38.41 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:19570
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A neomycin selection cassette replaced the entire coding sequence of the gene. (J:19570)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Cxcr2 Mutation:  8 strains or lines available
References
Original:  J:19570 Cacalano G, et al., Neutrophil and B cell expansion in mice that lack the murine IL-8 receptor homolog. Science. 1994 Jul 29;265(5172):682-4
All:  107 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory