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Cd8atm1Mak
Targeted Allele Detail
Nomenclature
Symbol: Cd8atm1Mak
Name: CD8 antigen, alpha chain; targeted mutation 1, Tak Mak
MGI ID: MGI:1857149
Synonyms: CD8-, CD8alpha-, CD8alpha-, Cd8atm1Mak, CD8KO, CD8 KO, CD8-KO, Lyt-2-
Gene: Cd8a  Location: Chr6:71373427-71379171 bp, + strand  Genetic Position: Chr6, 32.14 cM, cytoband C
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:68956
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (knock-out)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 5 strains available      Cell Lines: 0 lines available
Carrying any Cd8a Mutation:  15 strains or lines available
References
Original:  J:68956 Fung-Leung WP, et al., CD8 is needed for development of cytotoxic T cells but not helper T cells. Cell. 1991 May 3;65(3):443-9
All:  219 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory