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Targeted Allele Detail
Symbol: Bdkrb2tm1Jfh
Name: bradykinin receptor, beta 2; targeted mutation 1, J Fred Hess
MGI ID: MGI:1857135
Synonyms: B2-, B2-KO, B2R-, BdkrB2, Bk2r-, Bk B2R-, rB2 -
Gene: Bdkrb2  Location: Chr12:105563172-105593071 bp, + strand  Genetic Position: Chr12, 55.76 cM
Histological changes in the postischemic kidneys of wild type, Bdkrb2tm1Jfh/Bdkrb2tm1Jfh and MGI:3710159/MGI:3710159 mice

Show the 1 phenotype image(s) involving this allele.

Germline Transmission:  Earliest citation of germline transmission: J:25953
Parent Cell Line:  AB2.1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation details
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Bdkrb2 Mutation:  6 strains or lines available
Original:  J:25953 Borkowski JA, et al., Targeted disruption of a B2 bradykinin receptor gene in mice eliminates bradykinin action in smooth muscle and neurons. J Biol Chem. 1995 Jun 9;270(23):13706-10
All:  73 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 5.20
The Jackson Laboratory