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Tmc1dn
Spontaneous Allele Detail
Nomenclature
Symbol: Tmc1dn
Name: transmembrane channel-like gene family 1; deafness
MGI ID: MGI:1856845
Synonyms: dn
Gene: Tmc1  Location: Chr19:20783458-20954202 bp, - strand  Genetic Position: Chr19, 13.98 cM, cytoband B
Mutation
origin
Strain of Origin:  STOCK Grhl3ct/J
Mutation
description
Allele Type:    Spontaneous
Mutation:    Intragenic deletion
 
Mutation detailsThe mutation is a 1656 bp deletion including exon 14 and flanking intronic sequences. RT-PCR analysis confirmed that an mRNA was made that spliced exon 13 sequences in frame to exon 15 sequences. (J:75142)
Inheritance:    Recessive
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 1 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Tmc1 Mutation:  11 strains or lines available
References
Original:  J:236 Deol MS, et al., A new gene for deafness in the mouse. Heredity. 1958;12:463-6
All:  20 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/12/2015
MGI 5.21
The Jackson Laboratory