About   Help   FAQ
Dtnbp1sdy
Spontaneous Allele Detail
Nomenclature
Symbol: Dtnbp1sdy
Name: dystrobrevin binding protein 1; sandy
MGI ID: MGI:1856628
Synonyms: Dys-, Dys KO, sdy, sdy-
Gene: Dtnbp1  Location: Chr13:44922079-45002096 bp, - strand  Genetic Position: Chr13, 21.73 cM
Mutation
origin
Strain of Origin:  DBA/2J
Mutation
description
Allele Type:    Spontaneous
Mutation:    Intragenic deletion
 
Mutation detailsThe mutation in the sandy mouse has been attributed to a deletion in the Dtnbp1 gene from intron 5 nucleotide 3701 to intron 7 nucleotide 12377. The deletion results in the loss of 52 amino acids from position 119-172 and abolishes expression of the protein. Western analysis did not detect protein in hippocampus tissue from homozygous mutant mice. (J:85123, J:169460)
Inheritance:    Recessive
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Mice Carrying this Mutation: 4 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Dtnbp1 Mutation:  9 strains or lines available
References
Original:  J:14267 Sweet HO, Sandy (sdy). Mouse Genome. 1990;86:237
All:  31 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/07/2015
MGI 5.21
The Jackson Laboratory