Pstpip2^cmo
Spontaneous Allele Detail

Summary

• Symbol: Pstpip2^cmo
• Name: proline-serine-threonine phosphatase-interacting protein 2; chronic multifocal osteomyelitis
• MGI ID: MGI:1856595
• Synonyms: cmo
• Gene: Pstpip2 Location: Chr18:77882250-77971462 bp, + strand Genetic Position: Chr18, 52.38 cM, cytoband E3
• Alliance: Pstpip2^cmo page

Mutation origin

• Strain of Origin: C.D2-Qa2

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: Sequncing revealed a T-to-C transversion at coding nucleotide 293 that results in a highly conserved leucine to be replaced with a proline at amino acid position 98 (p.L98P). (J:104476)
• Inheritance: Recessive

Disease models

Expression

In Structures Affected by this Mutation:

9 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pstpip2 Mutation: 25 strains or lines available

References

• Original: J:1534 Byrd L, et al., Chronic multifocal osteomyelitis, a new recessive mutation on chromosome 18 of the mouse. Genomics. 1991 Dec;11(4):794-8
• All: 16 reference(s)