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A
Spontaneous Allele Detail
Nomenclature
Symbol: A
Name: nonagouti; wild-type agouti
MGI ID: MGI:1856464
Synonyms: dark-bellied agouti
Gene: a  Location: Chr2:154791402-155051012 bp, + strand  Genetic Position: Chr2, 76.83 cM
Mutation
origin
Strain of Origin:  various
Mutation
description
Allele Type:    Spontaneous
Mutation:    Other
 
Mutation detailsThis allele, often referred to as wild-type, comprises a novel 131 amino acid protein encoded in a gene comprising four exons, three coding, spanning 18kb. Unique changes in this gene account for all other alleles that have been molecularly characterized. The expression of this allele is almost always dominant to other alleles of this gene. (J:3523)
Inheritance:    Dominant
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 17 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 33 strains available      Cell Lines: 0 lines available
Carrying any a Mutation:  287 strains or lines available
Notes
The A allele is usually regarded as a wild-type allele. For example,the C3H and CBA mouse sublines are homozygous for agouti. Hairs are black with a subapical yellow band. This black-yellow-black pattern is referred to as agouti. The general appearance is yellowish brown, slightly lighter on the belly than on the back.

References
Original:  J:46318 Dry FW, The agouti coloration of the mouse (Mus Musculus) and the rat (Mus Norvegicus). J Genet. 1928;20:131-144
All:  21 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory