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DstTg4
Transgenic Allele Detail
Nomenclature
Symbol: DstTg4
Name: dystonin; transgene insertion 4
MGI ID: MGI:1856421
Synonyms: bullous pemphigoid antigen 1, 230kD, DstBpag1, dtTG4, Tg4
Gene: Dst  Location: Chr1:33908225-34308661 bp, + strand  Genetic Position: Chr1, 12.91 cM
Transgene
origin
Strain of Origin:  CD-1
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence, Modified isoform(s))
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsApproximately 15 copies of an Hsp68-lacZ transgene inserted into the genome, accompanied by a 45 kb deletion that removed the exons containing sequences for neural-specific alternative isoforms of the encoded protein. (J:17630, J:26733)
Inheritance:    Not Specified
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 12 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dst Mutation:  175 strains or lines available
References
Original:  J:17844 Kothary R, et al., A transgene containing lacZ inserted into the dystonia locus is expressed in neural tube. Nature. 1988 Sep 29;335(6189):435-7
All:  22 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/12/2021
MGI 6.16
The Jackson Laboratory