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Csf1op
Spontaneous Allele Detail
Nomenclature
Symbol: Csf1op
Name: colony stimulating factor 1 (macrophage); osteopetrosis
MGI ID: MGI:1856333
Synonyms: Csf-1op, Csf1- op, csfmop, Csfmop, M-, op
Gene: Csf1  Location: Chr3:107741048-107760469 bp, - strand  Genetic Position: Chr3, 46.83 cM, cytoband F3
Csf1op/Csf1op

Show the 3 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  B6;DW-Pou1f1dw
Mutation
description
Allele Type:    Spontaneous
Mutation:    Insertion
 
Mutation detailsA single nucleotide (T) insertion 262 bp downstream from the initiation codon resulted in a frameshift and the creation of a stop codon 21 bp downstream of the insertion. (J:10519)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 5 assay results
In Structures Affected by this Mutation: 39 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Csf1 Mutation:  6 strains or lines available
References
Original:  J:35678 Lane PW, Osteopetrosis (op). Mouse News Lett. 1973;48:35
All:  215 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory