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Csf1op
Spontaneous Allele Detail
Summary
Symbol: Csf1op
Name: colony stimulating factor 1 (macrophage); osteopetrosis
MGI ID: MGI:1856333
Synonyms: Csf-1op, Csf1- op, csfmop, Csfmop, M-, op
Gene: Csf1  Location: Chr3:107648364-107667785 bp, - strand  
Alliance: Csf1op page
Csf1op/Csf1op

Show the 3 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  B6;DW-Pou1f1dw
Mutation
description
Allele Type:    Spontaneous
Mutation:    Insertion
 
Mutation detailsA single nucleotide (T) insertion 262 bp downstream from the initiation codon resulted in a frameshift and the creation of a stop codon 21 bp downstream of the insertion. (J:10519)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 5 assay results
In Structures Affected by this Mutation: 38 anatomical structures
Tumor Data
List all tumor models in MMHCdb carrying Csf1op
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Csf1 Mutation:  28 strains or lines available
References
Original:  J:35678 Lane PW, Osteopetrosis (op). Mouse News Lett. 1973;48:35
All:  232 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/15/2022
MGI 6.22
The Jackson Laboratory