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Ank1nb
Spontaneous Allele Detail
Nomenclature
Symbol: Ank1nb
Name: ankyrin 1, erythroid; normoblastic anemia
MGI ID: MGI:1856298
Synonyms: nb, normoblastosis
Gene: Ank1  Location: Chr8:22974844-23150497 bp, + strand  Genetic Position: Chr8, 11.42 cM
Mutation
origin
Strain of Origin:  Non-inbred stock
Mutation
description
Allele Type:    Spontaneous
Mutation:    Intragenic deletion
 
Mutation detailsThis mutation arose in 1965 in a heterogeneous stock of mice maintained by Katherine P. Hummel at The Jackson Laboratory. A guanosine residue at position 4367 is deleted in exon 36 resulting in a frame shift mutation that introduces a premature stop 13 codons downstream and produces a truncated but functional protein. (J:10432, J:103074)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 9 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Ank1 Mutation:  56 strains or lines available
References
Original:  J:30699 Bernstein SE, Hereditary disorders of the rodent erythron, in Genetics in Laboratory Animal Medicine. 1969:9-33.
All:  26 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/12/2018
MGI 6.12
The Jackson Laboratory