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Yaa
Spontaneous Allele Detail
Nomenclature
Symbol: Yaa
Name: accelerated autoimmunity and lymphoproliferation transposition; accelerated autoimmunity and lymphoproliferation
MGI ID: MGI:1856277
Synonyms: Is(XOfd1-Mid1;Y)1Mp, Tp(X;Y)1Ekw
Gene: Yaa  Location: unknown  Genetic Position: ChrY, Syntenic
Mutation
origin
Strain of Origin:  SB/Le
Mutation
description
Allele Type:    Spontaneous
Mutations:    Insertion, Translocation
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 6 strains available      Cell Lines: 0 lines available
Carrying any Yaa Mutation:  9 strains or lines available
Notes
In congenic C57BL/6 Yaa mice expression of Tlr7 is increased 2-fold.

References
Original:  J:6235 Murphy ED, et al., A Y chromosome associated factor in strain BXSB producing accelerated autoimmunity and lymphoproliferation. Arthritis Rheum. 1979 Nov;22(11):1188-94
All:  65 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/15/2014
MGI 5.17
The Jackson Laboratory