Mbp^shi
Spontaneous Allele Detail

Summary

• Symbol: Mbp^shi
• Name: myelin basic protein; shiverer
• MGI ID: MGI:1856159
• Synonyms: shi
• Gene: Mbp Location: Chr18:82493271-82603762 bp, + strand Genetic Position: Chr18, 55.84 cM, cytoband E2-E4
• Alliance: Mbp^shi page

The Mbp^shi/Mbp^shi mouse

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: SWV

Mutation description

• Allele Type: Spontaneous
• Mutation: Intragenic deletion
• Mutation details: The shiverer mutation involves a large deletion from intron 1 to exon 6. The portion of the gene remaining includes exon 1 and 12.4-14.4 kb of intron 1 sequences. (J:7748, J:7925, J:20098, J:78561)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:	1 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available
• Carrying any Mbp Mutation: 30 strains or lines available

References

• Original: J:6578 Chernoff GF, Shiverer: an autosomal recessive mutant mouse with myelin deficiency. J Hered. 1981 Mar-Apr;72(2):128
• All: 124 reference(s)